1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide

• CAT Number: M122383
• CAS Number: 1892-57-5
• Molecular Formula: C8H17N3
• Molecular Weight: 155.24
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine
• InChI: InChI=1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3
• InChIKey: LMDZBCPBFSXMTL-UHFFFAOYSA-N
• SMILES: CCN=C=NCCCN(C)C

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide(CAT: M122383), often used as its hydrochloride salt (EDC or EDC·HCl), is a water-soluble carbodiimide coupling reagent with the molecular formula C₈H₁₇N₃. It is widely employed in peptide synthesis, protein conjugation, and nucleic acid labeling to activate carboxyl groups for amide or ester bond formation under mild conditions. Its tertiary amine functionality enhances solubility and reaction efficiency in aqueous or mixed solvent systems. Unlike some coupling agents, EDC produces soluble urea byproducts, simplifying purification. Its versatility and compatibility with biomolecules make it an essential tool in bioconjugation chemistry, pharmaceutical development, and biochemical research.