1-(3-Bromophenyl)-2,2-difluoroethanone

• CAT Number: L025106
• CAS Number: 1002356-02-6
• Molecular Formula: C8H5BrF2O
• Molecular Weight: 235.02
• Purity: ≥95%
• IUPAC Name: 1-(3-bromophenyl)-2,2-difluoroethanone
• InChI: InChI=1S/C8H5BrF2O/c9-6-3-1-2-5(4-6)7(12)8(10)11/h1-4,8H
• InChIKey: HZELFBPCXLKNMP-UHFFFAOYSA-N
• SMILES: C1=CC(=CC(=C1)Br)C(=O)C(F)F

1-(3-Bromophenyl)-2,2-difluoroethanone（Cat No.:L025106）is an aromatic ketone featuring a 3-bromophenyl ring attached to a 2,2-difluoroacetyl group. The presence of the bromine atom on the aromatic ring allows for further functionalization via cross-coupling reactions (e.g., Suzuki or Heck), while the difluoromethyl ketone moiety imparts strong electrophilic character and metabolic stability. This compound is a valuable building block in medicinal chemistry and agrochemical research, especially in the design of enzyme inhibitors, where the difluoroketone can mimic transition states or engage in hydrogen bonding. It is also useful in preparing fluorinated heterocycles and bioactive compounds.