1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride

• CAT Number: R042836
• CAS Number: 70918-74-0
• Molecular Formula: C13H17ClN2O3
• Molecular Weight: 284.74
• Purity: ≥95%
• Synonyms: USP Doxazosin Related Compound A; 1,4-Benzodioxin piperazine deriv.
• Storage: -20°C
• IUPAC Name: 2,3-dihydro-1,4-benzodioxin-3-yl(piperazin-1-yl)methanone;hydrochloride
• InChI: InChI=1S/C13H16N2O3.ClH/c16-13(15-7-5-14-6-8-15)12-9-17-10-3-1-2-4-11(10)18-12;/h1-4,12,14H,5-9H2;1H
• InChIKey: TUKBWYXLYINULI-UHFFFAOYSA-N
• SMILES: C1CN(CCN1)C(=O)C2COC3=CC=CC=C3O2.Cl

1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine monohydrochloride（Cat No.:R042836）is a hydrochloride salt of a benzodioxinyl-substituted piperazine derivative. The molecule features a 2,3-dihydro-1,4-benzodioxin moiety linked via a carbonyl group to the nitrogen of a piperazine ring, forming a stable amide bond. This compound is of interest in drug discovery, especially in the development of CNS-active agents and receptor modulators, due to its structural similarity to bioactive scaffolds. The piperazine core provides flexibility and solubility, while the benzodioxin fragment offers potential aromatic interactions in biological systems. The hydrochloride form improves stability and aqueous handling.