1-(2-HYDROXY-ETHYL)-PYRROLE-2,5-DIONE

• CAT Number: M048926
• CAS Number: 1585-90-6
• Molecular Formula: C6H7NO3
• Molecular Weight: 141.126
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 1-(2-hydroxyethyl)pyrrole-2,5-dione
• InChI: InChI=1S/C6H7NO3/c8-4-3-7-5(9)1-2-6(7)10/h1-2,8H,3-4H2
• InChIKey: AXTADRUCVAUCRS-UHFFFAOYSA-N
• SMILES: C1=CC(=O)N(C1=O)CCO

1-(2-Hydroxyethyl)-pyrrole-2,5-dione（Cat No.:M048926）, also known as N-(2-hydroxyethyl)maleimide, is a functionalized maleimide derivative featuring a hydroxyethyl side chain attached to the nitrogen atom of the pyrrole-2,5-dione ring. This compound is valued in bioconjugation and polymer chemistry due to its dual reactivity: the maleimide ring readily undergoes Michael addition with thiols, while the hydroxyl group enables further derivatization or crosslinking. It is widely used in the design of hydrogels, drug delivery systems, and surface modifications. Its balanced hydrophilicity and electrophilicity make it a useful intermediate in biomaterials and chemical biology.