For research use only. Not for therapeutic Use.
β-Amyloid (35-42)（Cat No.:I018318）is a synthetic peptide fragment derived from the C-terminal region of the amyloid-β protein, a hallmark molecule in Alzheimer’s disease pathology. This short peptide sequence readily aggregates into β-sheet–rich fibrils, serving as a key model for studying amyloid plaque formation, protein misfolding, and neurotoxicity. β-Amyloid (35-42) is widely applied in neuroscience, drug discovery, and Alzheimer’s disease research, enabling investigation into mechanisms of aggregation, oxidative stress, and neuronal damage. As a reference peptide, it is essential for developing therapeutic strategies targeting amyloid-related neurodegeneration.
| CAS Number | 183292-41-3 |
| Synonyms | (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]propanoic acid |
| Molecular Formula | C33H60N8O9S |
| Purity | ≥95% |
| IUPAC Name | (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]propanoic acid |
| InChI | InChI=1S/C33H60N8O9S/c1-11-19(8)27(32(48)37-20(9)33(49)50)41-31(47)26(18(6)7)40-30(46)25(17(4)5)38-23(43)15-35-22(42)14-36-29(45)24(16(2)3)39-28(44)21(34)12-13-51-10/h16-21,24-27H,11-15,34H2,1-10H3,(H,35,42)(H,36,45)(H,37,48)(H,38,43)(H,39,44)(H,40,46)(H,41,47)(H,49,50)/t19-,20-,21-,24-,25-,26-,27-/m0/s1 |
| InChIKey | WMASSBNUXWFHBX-CMCOHCKLSA-N |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](CCSC)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
