β,β-Dimethylacrylshikonin

• CAT Number: R072435
• CAS Number: 24502-79-2
• Molecular Formula: C21H22O6
• Molecular Weight: 370.40
• Purity: ≥95%
• Synonyms: [(1R)-1-(1,4-dihydroxy-5,8-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] 3-methylbut-2-enoate
• IUPAC Name: [(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] 3-methylbut-2-enoate
• InChI: InChI=1S/C21H22O6/c1-11(2)5-8-17(27-18(25)9-12(3)4)13-10-16(24)19-14(22)6-7-15(23)20(19)21(13)26/h5-7,9-10,17,22-23H,8H2,1-4H3/t17-/m1/s1
• InChIKey: BATBOVZTQBLKIL-QGZVFWFLSA-N
• SMILES: CC(=CC[C@H](C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)OC(=O)C=C(C)C)C

β,β-Dimethylacrylshikonin（Cat No.:R072435）is a naphthoquinone derivative isolated from the roots of Lithospermum erythrorhizon and related Boraginaceae plants, traditionally used in herbal medicine. Structurally, it features a shikonin backbone with a β,β-dimethylacryl substituent, contributing to its potent biological activities. Studies have demonstrated its anticancer, anti-inflammatory, and antimicrobial effects, with mechanisms involving apoptosis induction, inhibition of angiogenesis, and suppression of pro-inflammatory mediators. β,β-Dimethylacrylshikonin also shows promise in wound healing and skin-related therapies. Its multifunctional pharmacological profile makes it an attractive candidate for research into novel therapeutic agents.