(αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-benzeneacetic Acid

• CAT Number: R023917
• CAS Number: 33125-05-2
• Molecular Formula: C13H17NO4
• Molecular Weight: 251.28
• Purity: ≥95%
• Synonyms: (R)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-benzeneacetic acid; D-N-Carboxy-2-phenyl-glycine N-tert-butyl Ester; (2R)-2-(tert-Butoxycarbonylamino)-2-phenylethanoic Acid; (R)-2-((tert-Butoxycarbonyl)amino)-2-phenylacetic Acid; (R)-2-tert-Butoxycarbony
• Storage: -20°C
• IUPAC Name: (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-2-phenylacetic acid
• InChI: InChI=1S/C13H17NO4/c1-13(2,3)18-12(17)14-10(11(15)16)9-7-5-4-6-8-9/h4-8,10H,1-3H3,(H,14,17)(H,15,16)/t10-/m1/s1
• InChIKey: HOBFSNNENNQQIU-SNVBAGLBSA-N
• SMILES: CC(C)(C)OC(=O)NC(C1=CC=CC=C1)C(=O)O

(αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-benzeneacetic acid(CAT: R023917) is a chiral, Boc-protected derivative of L-phenylglycine, featuring a benzene ring attached to an α-amino acid backbone with an (R)-configuration. The Boc (tert-butoxycarbonyl) group protects the amino functionality, allowing selective manipulation of the carboxylic acid moiety during peptide synthesis or derivatization. This compound is widely used in asymmetric synthesis, peptide coupling, and pharmaceutical intermediate production. Its defined stereochemistry supports enantioselective applications and structure–activity relationship (SAR) studies. The molecule’s combination of aromatic, carboxyl, and protected amine groups makes it a valuable building block for the development of bioactive compounds and advanced materials.