(-)-α-Kainic Acid

• CAT Number: R015450
• CAS Number: 487-79-6
• Molecular Formula: C10H15NO4
• Molecular Weight: 213.23
• Purity: ≥95%
• Synonyms: (2S,3S,4S)-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid; 2-Carboxy-4-isopropenyl-3-pyrrolidineacetic Acid; (-)-Kainic Acid; (2S,3S,4S)-2-Carboxy-4-isopropenylpyrrolidine-3-acetic Acid; Digenic Acid; Digenin; Helminal; Kainic Acid; L-α-Kaini
• Target: Membrane Transporter/Ion Channel
• Solubility: >11.05mg/mL in DMSO
• Storage: Store at RT
• IUPAC Name: (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid
• InChI: InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
• InChIKey: VLSMHEGGTFMBBZ-OOZYFLPDSA-N
• SMILES: CC(=C)C1CNC(C1CC(=O)O)C(=O)O

(-)-α-Kainic Acid(CAT: R015450) is a potent neuroexcitatory amino acid derived from marine red algae, widely used as a research tool in neuroscience. Structurally similar to glutamate, it acts as a selective agonist for kainate receptors, a subtype of ionotropic glutamate receptors, making it essential for studying excitatory neurotransmission, synaptic plasticity, and neurotoxicity. (-)-α-Kainic Acid is commonly employed in animal models to induce seizures and mimic aspects of epilepsy and neurodegeneration. Its high receptor specificity enables detailed exploration of excitatory pathways and receptor pharmacology.