α-Bromo-γ-butyrolactone

• CAT Number: R004290
• CAS Number: 5061-21-2
• Molecular Formula: C4H5BrO2
• Molecular Weight: 164.99
• Purity: ≥95%
• Synonyms: 3-Bromodihydro-2(3H)-furanone; 2-Bromo-4-hydroxybutyric Acid-γ-lactone; 3-Bromotetrahydrofuran-2-one; NSC 11726; NSC 56959
• Storage: Store at -20°C
• IUPAC Name: 3-bromooxolan-2-one
• InChI: InChI=1S/C4H5BrO2/c5-3-1-2-7-4(3)6/h3H,1-2H2
• InChIKey: LFJJGHGXHXXDFT-UHFFFAOYSA-N
• SMILES: C1COC(=O)C1Br

α-Bromo-γ-butyrolactone(CAT: R004290) is a reactive halogenated lactone, featuring a bromine atom at the α-position of the γ-butyrolactone ring. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its electrophilic α-bromo functionality enables facile nucleophilic substitution, ring-opening, and alkylation reactions, making it a valuable building block for constructing heterocycles and functionalized lactone derivatives. Additionally, α-bromo-γ-butyrolactone is used in the synthesis of biologically active compounds and polymer precursors.