α-Arbutin

• CAT Number: R058603
• CAS Number: 84380-01-8
• Molecular Formula: C12H16O7
• Molecular Weight: 272.25
• Purity: 99%
• Synonyms: 4-Hydroxyphenyl-α-D-glucopyranoside; Hydroquinone O-α-D-Glucopyranoside
• Storage: -20°C
• Analysis method: HPLC and GC
• IUPAC Name: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
• InChI: InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1
• InChIKey: BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
• SMILES: C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O

α-Arbutin(CAT: R058603) is a glycosylated hydroquinone derivative known for its potent skin-brightening and depigmenting properties. It inhibits tyrosinase, the key enzyme in melanin synthesis, making it highly effective in reducing hyperpigmentation, age spots, and uneven skin tone. Compared to its β-isomer, α-Arbutin offers greater stability and efficacy with lower irritation potential, making it ideal for cosmetic and dermatological applications. It is commonly used in serums, creams, and lotions aimed at skin lightening and complexion improvement.