For research use only. Not for therapeutic Use.
(±)-LY367385（Cat No.:I031235）is a selective, competitive antagonist of the metabotropic glutamate receptor subtype 1 (mGluR1), part of the group I mGluRs involved in excitatory neurotransmission and synaptic plasticity. By selectively blocking mGluR1 without affecting mGluR5, (±)-LY367385 is widely used in neuroscience research to investigate the role of mGluR1 in learning, memory, pain, and neurodegenerative disorders. This racemic mixture modulates glutamatergic signaling and has been employed in models of epilepsy, Parkinson’s disease, and anxiety. Its specificity makes it a valuable pharmacological tool for dissecting mGluR1-mediated neuronal functions and signaling pathways.
| CAS Number | 198419-90-8 |
| Synonyms | 4-[amino(carboxy)methyl]-3-methylbenzoic acid |
| Molecular Formula | C10H11NO4 |
| Purity | ≥95% |
| IUPAC Name | 4-[amino(carboxy)methyl]-3-methylbenzoic acid |
| InChI | InChI=1S/C10H11NO4/c1-5-4-6(9(12)13)2-3-7(5)8(11)10(14)15/h2-4,8H,11H2,1H3,(H,12,13)(H,14,15) |
| InChIKey | SGIKDIUCJAUSRD-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC(=C1)C(=O)O)C(C(=O)O)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
