(±)-H3RESCA-TFP

• CAT Number: I045896
• CAS Number: 1919794-40-3
• Molecular Formula: C27H28F4N2O8
• Molecular Weight: 584.51
• Purity: ≥95%
• Synonyms: 2-[[(1R,2R)-2-[bis(carboxymethyl)amino]cyclohexyl]-[[4-[2-oxo-2-(2,3,5,6-tetrafluorophenoxy)ethyl]phenyl]methyl]amino]acetic acid
• InChI: InChI=1S/C27H28F4N2O8/c28-17-10-18(29)26(31)27(25(17)30)41-24(40)9-15-5-7-16(8-6-15)11-32(12-21(34)35)19-3-1-2-4-20(19)33(13-22(36)37)14-23(38)39/h5-8,10,19-20H,1-4,9,11-14H2,(H,34,35)(H,36,37)(H,38,39)/t19-,20-/m1/s1
• InChIKey: GKFBSFKLJKSHSZ-WOJBJXKFSA-N
• SMILES: C1CC[C@H]([C@@H](C1)N(CC2=CC=C(C=C2)CC(=O)OC3=C(C(=CC(=C3F)F)F)F)CC(=O)O)N(CC(=O)O)CC(=O)O

(±)-H3RESCA-TFP（Cat No.:I045896）is a heterobifunctional chemical probe incorporating a hydroxylamine-based RESCA moiety for site-specific protein labeling and a tetrafluorophenyl (TFP) ester group for efficient conjugation to amines. The racemic mixture (±) enhances versatility in biochemical applications. Its design enables stable and bioorthogonal linkage formation, making it highly useful in protein engineering, bioconjugation, and drug delivery studies. (±)-H3RESCA-TFP facilitates construction of antibody–drug conjugates, probes for imaging, and targeted therapeutics. It provides researchers with a flexible tool for exploring chemical biology, proteomics, and advanced therapeutic development.