γ-Lipoic Acid - CAS 462-20-4

Dihydrolipoic acid (DHLA; CAS 462-20-4) is a dithiol-containing carboxylic acid that is the reduced form of α-lipoic acid. It acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including hydroxyl radicals, peroxynitirite, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM. At concentrations of 50-100 µM, DHLA triggers apoptosis of mouse embryonic stem cells and human cancer cells, suppressing proliferation.

Catalog Number: R018565

CAS Number: 462-20-4

PubChem Substance ID:355436058

Molecular Formula: C8H16O2S2

Molecular Weight:208.334

Purity: ≥95%

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Synonym

Synonyms	6,8-Dimercaptooctanoic Acid; (±)-Dihydro-α-lipoic Acid; (±)-Dihydrolipoic Acid; DL-Dihydro-α-lipoic Acid; Dihydrolipoic Acid; Dihydrothioctic Acid; Reduced Lipoic Acid; Reduced Thioctic Acid; Dihydrothioctic Acid; dl-Dihydrolipoic Acid;

Property

Molecular Formula:	C8H16O2S2
Molecular Weight	208.334
Purity	≥95%
Storage	-20°C

Computed Descriptor

IUPAC Name	6,8-bis(sulfanyl)octanoic acid
InChI	InChI=1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10)
InChIKey	IZFHEQBZOYJLPK-UHFFFAOYSA-N
SMILES	C(CCC(=O)O)CC(CCS)S