α-Ergocryptine is a potent dopamine receptor agonist and prolactin inhibitor. It belongs to the ergot alkaloid class and is used in medicine to treat disorders related to high levels of prolactin, such as pituitary tumors and Parkinson’s disease. By acting on dopamine receptors, it regulates hormone levels and alleviates symptoms.
| Catalog Number | R050248 |
| CAS Number | 511-09-1 |
| Synonyms | (5’α)-12’-Hydroxy-2’-(1-methylethyl)-5’-(2-methylpropyl)ergotaman-3’,6’,18-trione; ?Ergocryptine; Ergokryptine; NSC 169479; NSC 407319; α-Ergocryptine; α-Ergokryptine; |
| Molecular Formula | C32H41N5O5 |
| Purity | 98 |
| Storage | Store at -20°C |
| IUPAC Name | (6aR,9R)-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide |
| InChI | InChI=1S/C32H41N5O5/c1-17(2)12-25-29(39)36-11-7-10-26(36)32(41)37(25)30(40)31(42-32,18(3)4)34-28(38)20-13-22-21-8-6-9-23-27(21)19(15-33-23)14-24(22)35(5)16-20/h6,8-9,13,15,17-18,20,24-26,33,41H,7,10-12,14,16H2,1-5H3,(H,34,38)/t20-,24-,25+,26+,31-,32+/m1/s1 |
| InChIKey | YDOTUXAWKBPQJW-NSLWYYNWSA-N |
| SMILES | CC(C)CC1C(=O)N2CCCC2C3(N1C(=O)C(O3)(C(C)C)NC(=O)C4CN(C5CC6=CNC7=CC=CC(=C67)C5=C4)C)O |
