(±)-JWH 018 N-(2-hydroxypentyl) metabolite

• CAT Number: R053748
• CAS Number: 1936529-84-8
• Molecular Formula: C24H23NO2
• Molecular Weight: 357.50
• Purity: ≥95%
• Synonyms: [1-(2-hydroxypentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone
• Storage: -20°C
• Related CAS: 1454924-71-0 1415744-43-2 1415744-44-3 941-98-0
• IUPAC Name: [1-(2-hydroxypentyl)indol-3-yl]-naphthalen-1-ylmethanone
• InChI: InChI=1S/C24H23NO2/c1-2-8-18(26)15-25-16-22(20-12-5-6-14-23(20)25)24(27)21-13-7-10-17-9-3-4-11-19(17)21/h3-7,9-14,16,18,26H,2,8,15H2,1H3
• InChIKey: ICOUPJBNCNTOKV-UHFFFAOYSA-N
• SMILES: CCCC(CN1C=C(C2=CC=CC=C21)C(=O)C3=CC=CC4=CC=CC=C43)O

(±)-JWH 018 N-(2-hydroxypentyl) metabolite（Cat No.:R053748）is a compound that results from the metabolism of JWH-018, a synthetic cannabinoid. JWH-018 is known for its psychoactive effects, binding to cannabinoid receptors in the brain. The N-(2-hydroxypentyl) metabolite forms when JWH-018 undergoes biotransformation, specifically through hydroxylation, and plays a role in understanding the drug’s pharmacokinetics and long-term effects. This metabolite is commonly studied in forensic toxicology and research on synthetic cannabinoids to monitor use and detect potential health risks associated with these substances, which are often abused for their cannabis-like effects.

Reference

1.Auwärter, V.,Dresen, S.,Weinmann, W., et al. “Spice” and other herbal blends: Harmless incense or cannabinoid designer drugs? Journal of Mass Spectrometry 44, 832-837 (2009).