ZWM026
ZWM026 is a multi-target inhibitor, and an indolocarbazoles analogue derived from mangrove in coastal marine wetland. ZWM026 exhibits selectivity and reversibility against T790M mutant over wild-type EGFR in naturally occurring NSCLC cells and constructed NIH-3T3 cells.
Catalog Number: I038787
Molecular Formula: C23H17N3O3
Molecular Weight:383.41
Purity: 98.0%
Appearance:Solid powder
* For research use only. Not for human or veterinary use.
Synonym
Synonyms | ZWM-026; ZWM 026; ZWM026 |
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Property
Molecular Formula: | C23H17N3O3 |
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Molecular Weight | 383.41 |
Solubility | Soluble in DMSO |
Purity | 98.0% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Computed Descriptor
IUPAC Name | 12-Ethyl-6-(hydroxymethyl)-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione |
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InChI | InChI=1S/C23H17N3O3/c1-2-25-15-10-6-4-8-13(15)17-19-18(22(28)26(11-27)23(19)29)16-12-7-3-5-9-14(12)24-20(16)21(17)25/h3-10,24,27H,2,11H2,1H3 |
InChIKey | ZYYKZAMVYVBWFE-UHFFFAOYSA-N |
SMILES | O=C1N(CO)C(C2=C1C3=C(C4=C2C5=C(N4CC)C=CC=C5)NC6=C3C=CC=C6)=O |