UNC 2400 - CAS 1433200-49-7

Negative control of UNC 1999. Exhibits 1000-fold lower potency than active analog (IC50 values are 62 and >200 μM for EZH1 and EZH2, respectively).

Catalog Number: I011054

CAS Number: 1433200-49-7

PubChem Substance ID:355432782

Molecular Formula: C35H47N7O2

Molecular Weight:597.808

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

SynonymsN-[(1,2-Dihydro-1,6-dimethyl-2-oxo-4-propyl-3-pyridinyl)methyl]-N-methyl-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide

Property

Molecular Formula: C35H47N7O2
Molecular Weight597.808
Target:Histone Methyltransferase
SolubilitySoluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
Purity≥95%
StorageStore at +4°C

Computed Descriptor

IUPAC NameN-[(1,6-dimethyl-2-oxo-4-propylpyridin-3-yl)methyl]-N-methyl-1-propan-2-yl-6-[6-(4-propan-2-ylpiperazin-1-yl)pyridin-3-yl]indazole-4-carboxamide
InChIInChI=1S/C35H47N7O2/c1-9-10-26-17-25(6)39(8)35(44)31(26)22-38(7)34(43)29-18-28(19-32-30(29)21-37-42(32)24(4)5)27-11-12-33(36-20-27)41-15-13-40(14-16-41)23(2)3/h11-12,17-21,23-24H,9-10,13-16,22H2,1-8H3
InChIKeyIFSQHIRDVVFJSQ-UHFFFAOYSA-N
SMILESCCCC1=C(C(=O)N(C(=C1)C)C)CN(C)C(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C(C)C)C(C)C