THP-PEG4-Pyrrolidine(N-Boc)-CH2OH - CAS 2378261-80-2
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523)[1].
PROTAC K-Ras Degrader-1 is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Catalog Number: I016932
CAS Number: 2378261-80-2
Molecular Formula: C₂₃H₄₃NO₉
Molecular Weight:477.59
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Property
Molecular Formula: | C₂₃H₄₃NO₉ |
---|---|
Molecular Weight | 477.59 |
Purity | ≥95% |