THP-PEG4-Pyrrolidine(N-Boc)-CH2OH - CAS 2378261-80-2

THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523)[1].
PROTAC K-Ras Degrader-1 is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Catalog Number: I016932

CAS Number: 2378261-80-2

Molecular Formula: C₂₃H₄₃NO₉

Molecular Weight:477.59

Purity: ≥95%

* For research use only. Not for human or veterinary use.


Property

Molecular Formula: C₂₃H₄₃NO₉
Molecular Weight477.59
Purity≥95%