TEMPOXIME - CAS 63467-53-8

a neuronal nicotinic AChR antagonist. Potent ganglioblocker. Hypotensive. Good penetration of biological membranes. Secondary analog of Pempoxime. Antioxidant, radical scavenger.

Piperidine derivative,9H18N2O. HCl–>, synthetic.

For comparative information see the attached 3 tables.

Cell permeant central nicotinic acetylcholine receptor blocker without action on skeleton muscle innervation.

Good to moderate penetration of biological membranes.
Antioxidant (precursor of stable TEMPO nitroxyl radical): together with PEMPOXIME can be used for testing the possibility of antioxydant contribution into any observed biological activity of TEMPOXIME.

Potential antimitotic (ask for the TEMPIDONE data).

Catalog Number: T000145

CAS Number: 63467-53-8

PubChem Substance ID:355427977

Molecular Formula: C9H19ClN2O

Molecular Weight:206.714

Purity: ≥95%

* For research use only. Not for human or veterinary use.


Synonyms2,2,6,6-tetramethylpiperidone-4 oxime hydrochloride.


Molecular Formula: C9H19ClN2O
Molecular Weight206.714
Solubilitywater, ethanol.
Storagestore at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 9.66 ml), stable for 1-2 days at 20C.

Computed Descriptor

IUPAC NameN-(2,2,6,6-tetramethylpiperidin-4-ylidene)hydroxylamine;hydrochloride