SD-208- CAS 627536-09-8

SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, > 100-fold selectivity over TGF-βRII.

Catalog Number: I013973

CAS Number: 627536-09-8

PubChem Substance ID:355050070

Molecular Formula: C₁₇H₁₀ClFN₆

Molecular Weight:352.75

Purity: ≥95%

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* For research use only. Not for human or veterinary use.


Property

Molecular Formula: C₁₇H₁₀ClFN₆
Molecular Weight352.75
Target: TGF-β Receptor
Solubility10 mM in DMSO
Purity≥95%

Computed Descriptor

IUPAC Name2-(5-chloro-2-fluorophenyl)-N-pyridin-4-ylpteridin-4-amine
InChIInChI=1S/C17H10ClFN6/c18-10-1-2-13(19)12(9-10)15-24-16-14(21-7-8-22-16)17(25-15)23-11-3-5-20-6-4-11/h1-9H,(H,20,22,23,24,25)
InChIKeyBERLXWPRSBJFHO-UHFFFAOYSA-N
SMILESC1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F