SB 204144 - CAS 141396-10-3
SB 204144 (Cat.No:I009305) is a chemical compound that acts as a selective antagonist of the 5-HT1B receptor, a subtype of serotonin receptors. It has been studied for its potential in the treatment of various neurological and psychiatric disorders, including migraine headaches and depression. SB 204144’s unique pharmacological profile makes it valuable in understanding serotonin receptor function and exploring therapeutic interventions.
Catalog Number: I009305
CAS Number: 141396-10-3
PubChem Substance ID:355201553
Molecular Formula: C42H51N4O8P
Molecular Weight:770.864
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Synonym
Synonyms | SB 204144; SB204144; SB-204144.;2,5,9,12-Tetraaza-7-phosphatridecanedioic acid, 7-hydroxy-3,11-bis(1-methylethyl)-4,10-dioxo-6,8-bis(phenylmethyl)-, bis(phenylmethyl) ester, 7-oxide, (3S-(3R*,6S*,8S*,11R*))- |
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Property
Molecular Formula: | C42H51N4O8P |
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Molecular Weight | 770.864 |
Solubility | Soluble in DMSO |
Purity | ≥95% |
Storage | 0 - 4 °C for short term, or -20 °C for long term |
Computed Descriptor
IUPAC Name | bis[(1R)-1-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-2-phenylethyl]phosphinic acid |
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InChI | InChI=1S/C42H51N4O8P/c1-29(2)37(45-41(49)53-27-33-21-13-7-14-22-33)39(47)43-35(25-31-17-9-5-10-18-31)55(51,52)36(26-32-19-11-6-12-20-32)44-40(48)38(30(3)4)46-42(50)54-28-34-23-15-8-16-24-34/h5-24,29-30,35-38H,25-28H2,1-4H3,(H,43,47)(H,44,48)(H,45,49)(H,46,50)(H,51,52)/t35-,36-,37+,38+/m1/s1 |
InChIKey | NKLAQVJZOVABOV-RNATXAOGSA-N |
SMILES | CC(C)C(C(=O)NC(CC1=CC=CC=C1)P(=O)(C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)OCC3=CC=CC=C3)O)NC(=O)OCC4=CC=CC=C4 |