SB 204144 - CAS 141396-10-3

SB 204144 (Cat.No:I009305) is a chemical compound that acts as a selective antagonist of the 5-HT1B receptor, a subtype of serotonin receptors. It has been studied for its potential in the treatment of various neurological and psychiatric disorders, including migraine headaches and depression. SB 204144’s unique pharmacological profile makes it valuable in understanding serotonin receptor function and exploring therapeutic interventions.

Catalog Number: I009305

CAS Number: 141396-10-3

PubChem Substance ID:355201553

Molecular Formula: C42H51N4O8P

Molecular Weight:770.864

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

SynonymsSB 204144; SB204144; SB-204144.;2,5,9,12-Tetraaza-7-phosphatridecanedioic acid, 7-hydroxy-3,11-bis(1-methylethyl)-4,10-dioxo-6,8-bis(phenylmethyl)-, bis(phenylmethyl) ester, 7-oxide, (3S-(3R*,6S*,8S*,11R*))-

Property

Molecular Formula: C42H51N4O8P
Molecular Weight770.864
SolubilitySoluble in DMSO
Purity≥95%
Storage0 - 4 °C for short term, or -20 °C for long term

Computed Descriptor

IUPAC Namebis[(1R)-1-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-2-phenylethyl]phosphinic acid
InChIInChI=1S/C42H51N4O8P/c1-29(2)37(45-41(49)53-27-33-21-13-7-14-22-33)39(47)43-35(25-31-17-9-5-10-18-31)55(51,52)36(26-32-19-11-6-12-20-32)44-40(48)38(30(3)4)46-42(50)54-28-34-23-15-8-16-24-34/h5-24,29-30,35-38H,25-28H2,1-4H3,(H,43,47)(H,44,48)(H,45,49)(H,46,50)(H,51,52)/t35-,36-,37+,38+/m1/s1
InChIKeyNKLAQVJZOVABOV-RNATXAOGSA-N
SMILESCC(C)C(C(=O)NC(CC1=CC=CC=C1)P(=O)(C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)OCC3=CC=CC=C3)O)NC(=O)OCC4=CC=CC=C4