Q Et - CAS 45732-65-8

Q Et is a rigid bicyclic analog of TMA and TEA. Molecular probe for calibration of the size of ion channels or receptors sites. Nicotinic AChR blocker. Acetylcholinesterase inhibitor. Lipid layers modifier.

Quaternary quinuclidine derivative,9H₁₈BrN–>, synthetic.

Nicotinic AChR : less active than Tetraethylammonium (TEA) and Tetramethylammonium (TMA) .

Acetylcholinesterase: TMA Ki =1.87 mM; TEA Ki =1.04 mM; QEt Ki =6.5 mM [2].

Catalog Number: T000110

CAS Number: 45732-65-8

PubChem Substance ID:355198916

Molecular Formula: C9H17N

Molecular Weight:139.242

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

• Synonyms: 1-ethyl quinicludinium bromide, N-ethyl quinuclidinium bromide.

Property

• Molecular Formula: C9H17N
• Molecular Weight: 139.242
• Solubility: water, ethanol.
• Purity: ≥95%
• Storage: store at room temperature in a dark place, in a dessicator (extremely hygroscopic). Solution for use: dissolve in water: 10-3M (2 mg in 9.09 ml), stable for 1-2 days at 20°C.

Computed Descriptor

• IUPAC Name: 4-ethyl-1-azabicyclo[2.2.2]octane
• InChI: InChI=1S/C9H17N/c1-2-9-3-6-10(7-4-9)8-5-9/h2-8H2,1H3
• InChIKey: ZLPCABMSTVWUGB-UHFFFAOYSA-N
• SMILES: CCC12CCN(CC1)CC2