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Pyroxamide

Pyroxamide

  • CAT Number: R039814
  • CAS Number: 382180-17-8
  • Molecular Formula: C13H19N3O3
  • Molecular Weight: 265.313
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Pyroxamide is a synthetic derivative of hydroxamic acid with antineoplastic properties, Pyroxamide inhibits histone deacetylases involved in transcription; induces hyperacetylation of core histones, modulating chromatin structure and affecting transcription of some genes that inhibit tumor growth; and induces growth arrest and apoptosis. Pyroxamide is used in clinical studies for cancer chemotherapy.

Catalog Number R039814
CAS Number 382180-17-8
Molecular Formula

C13H19N3O3

Purity 95%
Target HDAC
Solubility Soluble in DMSO > 10 mM
Storage Store at -20°C
IUPAC Name N/'-hydroxy-N-pyridin-3-yloctanediamide
InChI InChI=1S/C13H19N3O3/c17-12(15-11-6-5-9-14-10-11)7-3-1-2-4-8-13(18)16-19/h5-6,9-10,19H,1-4,7-8H2,(H,15,17)(H,16,18)
InChIKey PTJGLFIIZFVFJV-UHFFFAOYSA-N
SMILES C1=CC(=CN=C1)NC(=O)CCCCCCC(=O)NO

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