Picamilon - CAS 62936-56-5

Picamilon (CAS 62936-56-5) is a drug formed by a synthetic combination of niacin and γ-aminobutyric acid (GABA).  It can permeate the blood-brain barrier and then is hydrolyzed into GABA and niacin. The released GABA in theory would activate GABA receptors potentially producing an anxiolytic response.

Catalog Number: M003727

CAS Number: 62936-56-5

PubChem Substance ID:355195329

Molecular Formula: C10H11N2NaO3

Molecular Weight:230.199

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

Synonyms4-[(3-pyridinylcarbonyl)amino]-butanoic acid monosodium salt;SODIUM 4-PYRIDIN-3-YLCARBONYLAMINOBUTANOATE;SODIUM PIKAMILONE;NICOTINOYL-GABA SODIUM SALT;PICAMILON;PICAMILON SODIUM;PIKAMILONE SODIUM SALT;PIKAMILON SODIUM

Property

Molecular Formula: C10H11N2NaO3
Molecular Weight230.199
Purity≥95%
Storage-20°C
Overview of Clinical Research<span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;"><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">Picamilon was developed in the Soviet Union in 1969 and further studied in both Russia and Japan as a prodrug of GABA. In Russia, &nbsp;it&nbsp;</span><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">is sold as a prescription drug.</span></span></span>

Computed Descriptor

IUPAC Namesodium;4-(pyridine-3-carbonylamino)butanoate
InChIInChI=1S/C10H12N2O3.Na/c13-9(14)4-2-6-12-10(15)8-3-1-5-11-7-8;/h1,3,5,7H,2,4,6H2,(H,12,15)(H,13,14);/q;+1/p-1
InChIKeyDGWZSECHAXUHPD-UHFFFAOYSA-M
SMILESC1=CC(=CN=C1)C(=O)NCCCC(=O)[O-].[Na+]