Ofloxacin

  • CAT Number: A000867
  • CAS Number: 82419-36-1
  • Molecular Formula: C18H20FN3O4
  • Molecular Weight: 361.4
  • Purity: ≥95%
Inquiry Now

Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.

Catalog Number A000867
CAS Number 82419-36-1
Molecular Formula

C18H20FN3O4

Purity 95%
Target Topoisomerase
Solubility Limited solubility
Storage -20°C
InChI InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
InChIKey GSDSWSVVBLHKDQ-UHFFFAOYSA-N
SMILES CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
Reference

1: El-Zahry MR, Lendl B. Structure elucidation and degradation kinetic study of
Ofloxacin using surface enhanced Raman spectroscopy. Spectrochim Acta A Mol
Biomol Spectrosc. 2017 Dec 5;193:63-70. doi: 10.1016/j.saa.2017.12.007. [Epub
ahead of print] PubMed PMID: 29223055. <br />
2: Watson N, Gomez Serrano M, Selvadurai D. Topical ofloxacin use in G6PD
deficiency – safe or unsafe? Clin Otolaryngol. 2017 Dec 6. doi:
10.1111/coa.13043. [Epub ahead of print] PubMed PMID: 29210182. <br />
3: Lee H, Ahn S, Hwang NY, Jeon K, Kwon OJ, Huh HJ, Lee NY, Kim CK, Koh WJ.
Limited Effect of Later-generation Fluoroquinolones in the Treatment of
Ofloxacin-resistant and Moxifloxacin-susceptible Multidrug-resistant
Tuberculosis. Antimicrob Agents Chemother. 2017 Dec 4. pii: AAC.01784-17. doi:
10.1128/AAC.01784-17. [Epub ahead of print] PubMed PMID: 29203478. <br />
4: Kaur R, Kushwaha JP, Singh N. Electro-oxidation of Ofloxacin antibiotic by
dimensionally stable Ti/RuO(2) anode: Evaluation and mechanistic approach.
Chemosphere. 2017 Nov 16;193:685-694. doi: 10.1016/j.chemosphere.2017.11.065.
[Epub ahead of print] PubMed PMID: 29172159. <br />
5: Huang P, Ge C, Feng D, Yu H, Luo J, Li J, Strong PJ, Sarmah AK, Bolan NS, Wang
H. Effects of metal ions and pH on ofloxacin sorption to cassava residue-derived
biochar. Sci Total Environ. 2017 Oct 23. pii: S0048-9697(17)32888-7. doi:
10.1016/j.scitotenv.2017.10.177. [Epub ahead of print] PubMed PMID: 29074248. <br />
6: Bhattacharya A, Sharan R, Praharaj SK. High Dose Ofloxacin-induced Bimodal
Hallucinations in a 4 Years Old Child. Clin Psychopharmacol Neurosci. 2017 Nov
30;15(4):416-417. doi: 10.9758/cpn.2017.15.4.416. PubMed PMID: 29073756; PubMed
Central PMCID: PMC5678492. <br />
7: Jin H, Qi C, Zou Y, Kong Y, Ruan Z, Ding H, Xie X, Zhang J. Biochanin A
partially restores the activity of ofloxacin and ciprofloxacin against
topoisomerase IV mutation-associated fluoroquinolone-resistant Ureaplasma
species. J Med Microbiol. 2017 Nov;66(11):1545-1553. doi: 10.1099/jmm.0.000598.
Epub 2017 Oct 6. PubMed PMID: 28984242. <br />
8: Mirzajani R, Pourreza N, Burromandpiroze J. Fabrication of magnetic
Fe(3)O(4)@nSiO(2)@mSiO(2)-NH(2) core-shell mesoporous nanocomposite and its
application for highly efficient ultrasound assisted dispersive
μSPE-spectrofluorimetric detection of ofloxacin in urine and plasma samples.
Ultrason Sonochem. 2018 Jan;40(Pt A):101-112. doi:
10.1016/j.ultsonch.2017.06.027. Epub 2017 Jun 29. PubMed PMID: 28946397. <br />
9: Gouza A, Saoiabi S, El Karbane M, Masse S, Laurent G, Rami A, Saoiabi A,
Laghzizil A, Coradin T. Oil shale powders and their interactions with
ciprofloxacin, ofloxacin, and oxytetracycline antibiotics. Environ Sci Pollut Res
Int. 2017 Nov;24(33):25977-25985. doi: 10.1007/s11356-017-0100-5. Epub 2017 Sep
23. PubMed PMID: 28940003. <br />
10: Jin H, Tian X, Nie Y, Zhou Z, Yang C, Li Y, Lu L. Oxygen Vacancy Promoted
Heterogeneous Fenton-like Degradation of Ofloxacin at pH 3.2-9.0 by Cu
Substituted Magnetic Fe(3)O(4)@FeOOH Nanocomposite. Environ Sci Technol. 2017 Nov
7;51(21):12699-12706. doi: 10.1021/acs.est.7b04503. Epub 2017 Oct 17. PubMed
PMID: 28934546.

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!