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Metoprine

Metoprine

  • CAT Number: R051880
  • CAS Number: 7761-45-7
  • Molecular Formula: C11H10Cl2N4
  • Molecular Weight: 269.13
  • Purity: ≥95%
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Metoprine (Cat No.:R051880) is a diaminopyrimidine derivative that acts as a potent inhibitor of histamine N-methyltransferase (HMT). It can cross the blood-brain barrier, leading to increased levels of histamine in the brain by inhibiting HMT. Metoprine is recognized as an antifolate and antineoplastic drug. Its inhibition of HMT and subsequent modulation of histamine levels contribute to its therapeutic effects.

Catalog Number R051880
CAS Number 7761-45-7
Molecular Formula

C11H10Cl2N4

Purity 95%
Storage 2-8°C
IUPAC Name 5-(3,4-dichlorophenyl)-6-methylpyrimidine-2,4-diamine
InChI InChI=1S/C11H10Cl2N4/c1-5-9(10(14)17-11(15)16-5)6-2-3-7(12)8(13)4-6/h2-4H,1H3,(H4,14,15,16,17)
InChIKey VQJHOPSWBGJHQS-UHFFFAOYSA-N
SMILES CC1=C(C(=NC(=N1)N)N)C2=CC(=C(C=C2)Cl)Cl

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