Lomitapide - CAS 182431-12-5
Lomitapide is a MTP inhibitor. Lomitapid is a novel agent for the treatment of homozygous familial hypercholesterolemia. Lomitapide is an orally active inhibitor of microsomal triglyceride transfer protein that is indicated as an adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available for the reduction of LDL-C, total cholesterol, apolipoprotein B, and non-high-density lipoprotein cholesterol in adult patients with HoFH.
Catalog Number: A000126
CAS Number: 182431-12-5
PubChem Substance ID:355038163
Molecular Formula: C₃₉H₃₇F₆N₃O₂
Molecular Weight:693.72
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Synonym
Synonyms | 182431-12-5; Juxtapid; Lojuxta; BMS-201038; AEGR 733 |
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Property
Molecular Formula: | C₃₉H₃₇F₆N₃O₂ |
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Molecular Weight | 693.72 |
Target: | MTP inhibitor |
Purity | ≥95% |
Storage | -20°C |
Computed Descriptor
InChI | InChI=1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-17-27(18-16-26)39(43,44)45/h1-6,9-18,28H,7-8,19-25H2,(H,46,50)(H,47,49) |
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InChIKey | MBBCVAKAJPKAKM-UHFFFAOYSA-N |
SMILES | C1CN(CCC1NC(=O)C2=CC=CC=C2C3=CC=C(C=C3)C(F)(F)F)CCCCC4(C5=CC=CC=C5C6=CC=CC=C64)C(=O)NCC(F)(F)F |