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CAS No.: 547756-93-4
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| Product Details | |
|---|---|
For research use only. Not Intended for Therapeutic Use! |
|
| Cat No: | I010544 |
| Synonyms: | 1-[1,3-Dimethyl-4-(2-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-4-(3,5-dichloro-4-pyridinyl)-semicarbazide |
| Molecular Formula: | C17H19N7OCl2 |
| Molecular Weight: | 408.29 |
| Description: | Sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P2 (EDG-5). Inhibits S1P binding to human S1P2 receptors with an IC50 value of 17.6 nM. |
| Price: | Get quote |
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Sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P2 (EDG-5). Inhibits S1P binding to human S1P2 receptors with an IC50 value of 17.6 nM. At concentrations up to 10 μM, displays 4.2% inhibition of S1P3 and does not antagonize S1P1. Enhances S1P-induced angiogenesis in vivo.
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