Isoproterenol-d7 HCl - CAS 2517584-04-0

Isoproterenol-d7 is intended for use as an internal standard for the quantification of isoproterenol by GC- or LC-MS. Isoproterenol is an agonist of β1- and β2-adrenergic receptors (β1- and β2-ARs; Kis = 224 and 458 nM, respectively). It is selective for β1- and β2-ARs over β3-ARs (Ki = 1,570 nM). Isoproterenol inhibits contractions in isolated field-stimulated rat vas deferens (EC50 = 45.6 nM). In vivo, isoproterenol (0.33 mg/kg) decreases blood pressure and increases water intake in nephrectomized rats. It reduces blood pressure and increases heart rate in renal hypertensive rabbits. Isoproterenol inhibits histamine-induced bronchospasms in anesthetized dogs. Formulations containing isoproterenol have been used in the treatment of bradydysrhythmias and to improve breathing during anesthesia.

Catalog Number: I029594

CAS Number: 2517584-04-0

Molecular Formula: C11H11D7ClNO3

Molecular Weight:254.7617

Purity: 98.0%

Appearance:Solid powder

* For research use only. Not for human or veterinary use.

Synonym

SynonymsIsoproterenol-d7 HCl; Isoproterenol d7 HCl; Isoproterenol d7 hydrochloride; Isoproterenol-d7 hydrochloride;

Property

Molecular Formula: C11H11D7ClNO3
Molecular Weight254.7617
SolubilityTo be determined
Purity98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Computed Descriptor

IUPAC Name4-(1-hydroxy-2-((propan-2-yl-d7)amino)ethyl)benzene-1,2-diol hydrochloride
InChIInChI=1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H/i1D3,2D3,7D;
InChIKeyIROWCYIEJAOFOW-AUYCXRIESA-N
SMILES[2H]C([2H])(C([2H])(NCC(O)C1=CC(O)=C(O)C=C1)C([2H])([2H])[2H])[2H].Cl