HsTx-1 is a member of the a-KTx6 family of scorpion toxins active on voltage-gated Kv1.3 channels (Kd close to 10 pM). HsTx-1 is also very active on Kv1.1 channels (IC50 around 7 nM). It is however inactive on apamin-sensitive SK channels. It is one of the most potent toxins active on Kv1.3 channel.
* For research use only. Not for human or veterinary use.
|Molecular Weight||3819.87 Da|
|Target:||Selective blocker of Kv1.3 channel|