HRN 00430

• CAT Number: I028889
• Molecular Formula: C16H22N4O10
• Molecular Weight: 430.37
• Purity: 90%
• Solubility: Soluble in DMSO
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (3S,4R,5S,6R)-6-(acetoxymethyl)-3-(2-azidoacetamido)tetrahydro-2H-pyran-2,4,5-triyl triacetate
• InChI: InChI=1S/C16H22N4O10/c1-7(21)26-6-11-14(27-8(2)22)15(28-9(3)23)13(16(30-11)29-10(4)24)19-12(25)5-18-20-17/h11,13-16H,5-6H2,1-4H3,(H,19,25)/t11-,13+,14?,15?,16?/m1/s1
• InChIKey: HGMISDAXLUIXKM-RJOKEUQMSA-N
• SMILES: O=C(CN=[N+]=[N-])N[C@H]1[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)OC1OC(C)=O

HRN 00430, also known as N-azidoacetylmannosamine-tretraacylated (Ac4ManNAz) is a biochemical that may be used for in vivo cell labeling and tracking and, therefore, may be useful for cell-based therapy for monitoring the efficacy of molecule delivery and the fate of recipient cells. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Reference

1: Han SS, Lee DE, Shim HE, Lee S, Jung T, Oh JH, Lee HA, Moon SH, Jeon J, Yoon S, Kim K, Kang SW. Physiological Effects of Ac4ManNAz and Optimization of Metabolic Labeling for Cell Tracking. Theranostics. 2017 Mar 1;7(5):1164-1176. doi: 10.7150/thno.17711. eCollection 2017. PubMed PMID: 28435456; PubMed Central PMCID: PMC5399584.