Fosamprenavir Calcium - CAS 226700-81-8 (calcium)
Fosamprenavir Calcium Salt is a HIV protease inhibitor that is water soluble prodrug of amprenavir. Fosamprenavir Calcium is the calcium salt form of fosamprenavir, prodrug of amprenavir with antiviral property. Fosamprenavir is converted to amprenavir by cellular phosphatases in the epithelial cells of the intestine.
Catalog Number: I006846
CAS Number: 226700-81-8 (calcium)
PubChem Substance ID:355169401
Molecular Formula: C25H34CaN3O9PS
Molecular Weight:623.671
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Synonym
Synonyms | Fosamprenavir Calcium; Lexiva; GW433908G; Amprenavir phosphate calcium; UNII-ID1GU2627N; GW 433908; GW 433908G; GW 908; GW-433908; GW-433908G; GW-908;;calcium;[(2R,3S)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3S)-oxolan-3-yl]oxycarbonyl |
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Property
Molecular Formula: | C25H34CaN3O9PS |
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Molecular Weight | 623.671 |
Target: | HIV Protease Inhibitor |
Solubility | Soluble in DMSO, not in water |
Purity | ≥95% |
Storage | 0 - 4°C for short term or -20 °C for long term |
Computed Descriptor
IUPAC Name | calcium;[(2R,3S)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3S)-oxolan-3-yl]oxycarbonylamino]-4-phenylbutan-2-yl] phosphate |
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InChI | InChI=1S/C25H36N3O9PS.Ca/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21;/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32);/q;+2/p-2/t21-,23-,24+;/m0./s1 |
InChIKey | PMDQGYMGQKTCSX-HQROKSDRSA-L |
SMILES | CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2] |