Fosamprenavir Calcium - CAS 226700-81-8 (calcium)

Fosamprenavir Calcium Salt is a HIV protease inhibitor that is water soluble prodrug of amprenavir. Fosamprenavir Calcium is the calcium salt form of fosamprenavir, prodrug of amprenavir with antiviral property. Fosamprenavir is converted to amprenavir by cellular phosphatases in the epithelial cells of the intestine.

Catalog Number: I006846

CAS Number: 226700-81-8 (calcium)

PubChem Substance ID:355169401

Molecular Formula: C25H34CaN3O9PS

Molecular Weight:623.671

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

SynonymsFosamprenavir Calcium; Lexiva; GW433908G; Amprenavir phosphate calcium; UNII-ID1GU2627N; GW 433908; GW 433908G; GW 908; GW-433908; GW-433908G; GW-908;;calcium;[(2R,3S)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3S)-oxolan-3-yl]oxycarbonyl

Property

Molecular Formula: C25H34CaN3O9PS
Molecular Weight623.671
Target:HIV Protease Inhibitor
SolubilitySoluble in DMSO, not in water
Purity≥95%
Storage0 - 4°C for short term or -20 °C for long term

Computed Descriptor

IUPAC Namecalcium;[(2R,3S)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3S)-oxolan-3-yl]oxycarbonylamino]-4-phenylbutan-2-yl] phosphate
InChIInChI=1S/C25H36N3O9PS.Ca/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21;/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32);/q;+2/p-2/t21-,23-,24+;/m0./s1
InChIKeyPMDQGYMGQKTCSX-HQROKSDRSA-L
SMILESCC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2]