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Clindamycin hydrochloride

Clindamycin hydrochloride

  • CAT Number: A000180
  • CAS Number: 21462-39-5
  • Molecular Formula: C₁₈H₃₃ClN₂O₅S · HCl
  • Molecular Weight: 461.44
  • Purity: 98%
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Clindamycin hydrochloride is a salt of clindamycin, a semi-synthetic lincosamide. The hydrochloride salt forms at the basic Nethylproline moiety and is the preferred pharmaceutical formulation. Like other members of the lincosamide family, clindamycin
is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin hydrochloride acts by
binding to the 23S ribosomal subunit, blocking protein synthesis. Clindamycin hydrochloride has been extensively studied with
over 8,000 literature citations.

Catalog Number A000180
CAS Number 21462-39-5
Molecular Formula

C₁₈H₃₃ClN₂O₅S · HCl

Purity 98
Target 50S ribosomal
Storage 3 years -20C powder
Analysis method HPLC
InChI InChI=1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1
InChIKey AUODDLQVRAJAJM-XJQDNNTCSA-N
SMILES CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl.Cl
Reference

<p>
Lovmar, Martin, and Tanel Tenson. /The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome./<em>Journal of Molecular Microbiology</em> 330.5 (2003): 1005-014.</p>
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