InChI | 1S/C21H26ClNO.C4H4O4/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2;5-3(6)1-2-4(7)8/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t20-,21-;/m1./s1 |
Reference | 1: Green AJ, Gelfand JM, Cree BA, Bevan C, Boscardin WJ, Mei F, Inman J, Arnow S,
Devereux M, Abounasr A, Nobuta H, Zhu A, Friessen M, Gerona R, von Büdingen HC,
Henry RG, Hauser SL, Chan JR. Clemastine fumarate as a remyelinating therapy for
multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover
trial. Lancet. 2017 Dec 2;390(10111):2481-2489. doi:
10.1016/S0140-6736(17)32346-2. Epub 2017 Oct 10. PubMed PMID: 29029896.
<br>
2: Cohen JA, Tesar PJ. Clemastine fumarate for promotion of optic nerve
remyelination. Lancet. 2017 Dec 2;390(10111):2421-2422. doi:
10.1016/S0140-6736(17)32639-9. Epub 2017 Oct 10. PubMed PMID: 29029894.
<br>
3: Turner RB, Sperber SJ, Sorrentino JV, O/’Connor RR, Rogers J, Batouli AR,
Gwaltney JM Jr. Effectiveness of clemastine fumarate for treatment of rhinorrhea
and sneezing associated with the common cold. Clin Infect Dis. 1997
Oct;25(4):824-30. PubMed PMID: 9356796.
<br>
4: Gwaltney JM Jr, Park J, Paul RA, Edelman DA, O/’Connor RR, Turner RB.
Randomized controlled trial of clemastine fumarate for treatment of experimental
rhinovirus colds. Clin Infect Dis. 1996 Apr;22(4):656-62. PubMed PMID: 8729205.
<br>
5: Sipinen SA, Kulvik M, Leiniö M, Viljanen A, Lindholm H. Neuropsychologic and
cardiovascular effects of clemastine fumarate under pressure. Undersea Hyperb
Med. 1995 Dec;22(4):401-6. PubMed PMID: 8574128.
<br>
6: Miller WH Jr, Scott DW. Clemastine fumarate as an antipruritic agent in
pruritic cats: results of an open clinical trial. Can Vet J. 1994
Aug;35(8):502-4. PubMed PMID: 7954223; PubMed Central PMCID: PMC1686718.
<br>
7: Bedair MM, Korany MA, Issa AS. Derivative spectrophotometric determination of
clemastine fumarate in pharmaceutical preparations. Analyst. 1988
Jul;113(7):1137-8. PubMed PMID: 3223589.
<br>
8: Jolliffe DS, Sim-Davis D, Templeton JS. A placebo-controlled comparative study
of sustained-release brompheniramine maleate against clemastine fumarate in the
treatment of chronic urticaria. Curr Med Res Opin. 1985;9(6):394-9. PubMed PMID:
3886304.
<br>
9: Okuda M. Clinical investigation of ketotifen in perennial allergic rhinitis: a
double-blind comparative study of ketotifen and clemastine fumarate. Rhinology.
1984 Sep;22(3):171-82. PubMed PMID: 6390659.
<br>
10: Dockhorn RJ, Oggel JD. Clemastine fumarate for symptomatic relief of allergic
rhinitis. Mo Med. 1982 Nov;79(11):748-50. PubMed PMID: 7177096.
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