BMT-124110 - CAS 1679371-59-5
BMT-124110 is a potent, selective AAK1 inhibitor with an IC50 of 0.9 nM. BMT-124110 shows antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 17 and 99 nM, respectively[1].
BMT-124110 shows a cellular IC50 of 3.2±1.4 nM for AAK1[1].
BMT-124110 is added directly onto the spinal corevd by microiontophoresis, leading to reduction in windup-induced activity in 10 of 14 animals[1].
Catalog Number: I016211
CAS Number: 1679371-59-5
Molecular Formula: C₂₁H₂₇N₃O₃
Molecular Weight:369.46
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Property
Molecular Formula: | C₂₁H₂₇N₃O₃ |
---|---|
Molecular Weight | 369.46 |
Purity | ≥95% |