Avibactam sodium - CAS 1192491-61-4

Avibactam (CAS 1192491-61-4), which is the first non-β-lactam β-lactamase inhibitor to be introduced for clinical use, is a broad-spectrum serine β-lactamase inhibitor with activity against class A, class C, and, some, class D β-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. 

Catalog Number: I003307

CAS Number: 1192491-61-4

PubChem Substance ID:355038153

Molecular Formula: C7H10N3NaO6S

Molecular Weight:287.23

Purity: ≥95%

* For research use only. Not for human or veterinary use.


SynonymsNXL104; NXL-104; NXL 104; Avibactam; Avibactam sodium.;sodium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate


Molecular Formula: C7H10N3NaO6S
Molecular Weight287.23
Target:non-β-lactam β-lactamase inhibitor
SolubilitySoluble in DMSO, not in water
Storage0 - 4 °C for short term or -20 °C for long term
Related CAS.1192500-31-4 ( Avibactam free acid)
Overview of Clinical Research<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Avibactam is a b<span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">eta lactamase inhibitor and a cell wall inhibitor.&nbsp;</span></span></span><span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;"><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">Antimicrobial data from in vitro studies in Enterobacteriaceae and P. aeruginosa isolates presented at the IDWeek 2020 (IDW-2020)</span></span></span></span>

Computed Descriptor

IUPAC Namesodium;[(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] sulfate