Ascochlorin - CAS 26166-39-2

Ascochlorin is an antitumor fungal metabolite with antitumor and antiviral properties.

Ascochlorin specifically inhibits matrix metalloproteinase-9 (MMP-9) activity through suppression of activator protein-1 (AP-1)-dependent induction of MMP-9 gene expression. Via AP-1 suppression, ascochlorin selectively kills MX-1 cells, a human breast cancer cell line lacking estrogen receptors.

Catalog Number: R003136

CAS Number: 26166-39-2

Molecular Formula: C23H29CIO4

Molecular Weight:404.9

Purity: ≥95%

Appearance:White Powder

* For research use only. Not for human or veterinary use.

Synonym

SynonymsAntibiotic LL-Z1272γ;Ilicicolin D;NSC 287492

Property

Molecular Formula: C23H29CIO4
Molecular Weight404.9
Purity≥95%
Storage-20°C

Computed Descriptor

IUPAC Name5-chloro-2,4-dihydroxy-6-methyl-3-[(2E,4E)-3-methyl-5-[(1R,2R,6R)-1,2,6-trimethyl-3-oxocyclohexyl]penta-2,4-dienyl]benzaldehyde
InChIInChI=1S/C23H29ClO4/c1-13(10-11-23(5)14(2)7-9-19(26)16(23)4)6-8-17-21(27)18(12-25)15(3)20(24)22(17)28/h6,10-12,14,16,27-28H,7-9H2,1-5H3/b11-10+,13-6+/t14-,16+,23+/m1/s1
InChIKeySETVRSKZJJWOPA-FLDGXQSCSA-N
SMILESCC1CCC(=O)C(C1(C)C=CC(=CCC2=C(C(=C(C(=C2O)Cl)C)C=O)O)C)C