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CAS No.: 80-50-2
PubChem Substance ID: 355144679
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| Product Details | |
|---|---|
For research use only. Not Intended for Therapeutic Use! | |
| Cat No: | R016084 |
| Synonyms: | (3-endo)-8,8-Dimethyl-3-[(1-oxo-2-propylpentyl)oxy]-8-azoniabicyclo[3.2.1]octane Bromide; 3α-Hydroxy-8-methyl-1αH,5αH-tropanium Bromide 2-Propylvalerate; endo-8,8-Dimethyl-3-[(1-oxo-2-propylpentyl)oxy]- 8-azoniabicyclo[3.2.1]octane Bromide; 8-Methylt |
| Molecular Formula: | C17H32BrNO2 |
| Molecular Weight: | 362.352 |
| Description: | Octatropine methylbromide (INN) or anisotropine methylbromide (USAN), trade names Valpin, Endovalpin, Lytispasm and others, is a muscarinic antagonist and antispasmodic. It was introduced to the U.S. |
| Price: | Get quote |
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Octatropine methylbromide (INN) or anisotropine methylbromide (USAN), trade names Valpin, Endovalpin, Lytispasm and others, is a muscarinic antagonist and antispasmodic. It was introduced to the U.S. market in 1963 as an adjunct in the treatment of peptic ulcer, and promoted as being more specific to the gastrointestinal tract than other anticholinergics. Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant action on the bile ducts and gallbladder. In general, smaller doses of anisotropine methylbromide inhibit salivary and bronchial secretions, sweating, and accommodation; cause dilatation of the pupil; and increase the heart rate. Larger doses are required to decrease motility of the gastrointestinal and urinary tracts and to inhibit gastric acid secretion.
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