ADWX-1

ADWX-1 is an optimised synthetic analog of the scorpion peptide BmKTx. ADWX-1 is known to block voltage-gated Kv1.3 channel with a high affinity (IC50 = 1.89 pM) and selectivity (340 fold greater affinity than for voltage-dependent ). ADWX-1 inhibits CD4+ CCR7– T-cell proliferation. ADWX-1 is an interesting therapeutic candidate to treat auto-immune disorders such as multiple sclerosis, type-1 diabetes, rheumatoid arthritis and psoriasis. This peptide is a valuable tool for studying the structure-function of Kv1.3 channel and auto-immunity pathways.

Catalog Number: P000379

Molecular Formula: C169H281N57O46S7

Molecular Weight:4071.90 Da

Purity: ≥95%

* For research use only. Not for human or veterinary use.


Property

Molecular Formula: C169H281N57O46S7
Molecular Weight4071.90 Da
Target:Kv1.3 channel blocker
Purity≥95%
StorageRT