ADWX-1
ADWX-1 is an optimised synthetic analog of the scorpion peptide BmKTx. ADWX-1 is known to block voltage-gated Kv1.3 channel with a high affinity (IC50 = 1.89 pM) and selectivity (340 fold greater affinity than for voltage-dependent ). ADWX-1 inhibits CD4+ CCR7– T-cell proliferation. ADWX-1 is an interesting therapeutic candidate to treat auto-immune disorders such as multiple sclerosis, type-1 diabetes, rheumatoid arthritis and psoriasis. This peptide is a valuable tool for studying the structure-function of Kv1.3 channel and auto-immunity pathways.
Catalog Number: P000379
Molecular Formula: C169H281N57O46S7
Molecular Weight:4071.90 Da
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Property
Molecular Formula: | C169H281N57O46S7 |
---|---|
Molecular Weight | 4071.90 Da |
Target: | Kv1.3 channel blocker |
Purity | ≥95% |
Storage | RT |