Reference | </br>1:A sirtuin activator and an anti-inflammatory molecule-multifaceted roles of adjudin and its potential applications for aging-related diseases. Xia W, Geng K.Semin Cell Dev Biol. 2016 Nov;59:71-78. doi: 10.1016/j.semcdb.2016.07.020. Epub 2016 Jul 20. Review. PMID: 27450234 </br>2:Effective Delivery of Male Contraceptives Behind the Blood-Testis Barrier (BTB) – Lesson from Adjudin. Chen H, Mruk DD, Xia W, Bonanomi M, Silvestrini B, Cheng CY.Curr Med Chem. 2016;23(7):701-13. Review. PMID: 26758796 Free PMC Article</br>3:Adjudin–A Male Contraceptive with Other Biological Activities. Cheng YH, Xia W, Wong EW, Xie QR, Shao J, Liu T, Quan Y, Zhang T, Yang X, Geng K, Silvestrini B, Cheng CY.Recent Pat Endocr Metab Immune Drug Discov. 2015;9(2):63-73. Review. PMID: 26510796 </br>4:Combination delivery of Adjudin and Doxorubicin <i>via</i> integrating drug conjugation and nanocarrier approaches for the treatment of drug-resistant cancer cells. Li X, Gao C, Wu Y, Cheng CY, Xia W, Zhang Z.J Mater Chem B Mater Biol Med. 2015 Feb 28;3(8):1556-1564. Epub 2015 Jan 2. PMID: 27182439 Free PMC Article</br>5:Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway. Quan Y, Xia L, Shao J, Yin S, Cheng CY, Xia W, Gao WQ.Sci Rep. 2015 Feb 2;5:8181. doi: 10.1038/srep08181. PMID: 25640330 Free PMC Article</br>6:Interaction of oligomeric breast cancer resistant protein (BCRP) with adjudin: a male contraceptive with anti-cancer activity. Cheng YH, Jenardhanan P, Mathur PP, Qian X, Xia W, Silvestrini B, Cheng CY.Curr Mol Pharmacol. 2014;7(2):147-53. Review. PMID: 25620224 Free PMC Article</br>7:Adjudin protects against cerebral ischemia reperfusion injury by inhibition of neuroinflammation and blood-brain barrier disruption. Liu T, Zhang T, Yu H, Shen H, Xia W.J Neuroinflammation. 2014 Jun 14;11:107. doi: 10.1186/1742-2094-11-107. PMID: 24927761 Free PMC Article</br>8:Adjudin disrupts spermatogenesis by targeting drug transporters: Lesson from the breast cancer resistance protein (BCRP). Qian X, Cheng YH, Jenardhanan P, Mruk DD, Mathur PP, Xia W, Silvestrini B, Cheng CY.Spermatogenesis. 2013 Apr 1;3(2):e24993. PMID: 23885306 Free PMC Article</br>9:Role of P-glycoprotein at the blood-testis barrier on adjudin distribution in the testis: a revisit of recent data. Su L, Jenardhanan P, Mruk DD, Mathur PP, Cheng YH, Mok KW, Bonanomi M, Silvestrini B, Cheng CY.Adv Exp Med Biol. 2012;763:318-33. PMID: 23397632 Free PMC Article</br>10:Male contraceptive Adjudin is a potential anti-cancer drug. Xie QR, Liu Y, Shao J, Yang J, Liu T, Zhang T, Wang B, Mruk DD, Silvestrini B, Cheng CY, Xia W.Biochem Pharmacol. 2013 Feb 1;85(3):345-55. doi: 10.1016/j.bcp.2012.11.008. Epub 2012 Nov 23. PMID: 23178657 Free PMC Article
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