PROTOPINE HCl


CAS No. : 6164-47-2

PROTOPINE HCl,6164-47-2
Product Details
Cat No:T000140
Molecular Formula:C20H20ClNO5
Molecular Weight:389.832
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Purity:≥ 98 %
Cat No:T000140
Cas No:6164-47-2
Product-Name:PROTOPINE HCl
InChI:InChI=1S/C20H19NO5.ClH/c1-21-5-4-13-7-18-19(25-10-24-18)8-14(13)16(22)6-12-2-3-17-20(15(12)9-21)26-11-23-17;/h2-3,7-8H,4-6,9-11H2,1H3;1H
InChIKey:NWNVDSJZGYDVQW-UHFFFAOYSA-N
SMILES:CN1CCC2=CC3=C(C=C2C(=O)CC4=C(C1)C5=C(C=C4)OCO5)OCO3.Cl

It is a Ca2+ channel blocker; antiplatelet agent, a GABA binding activator.
It is also an antiarrhythmic with complex mechanism of action.


Alkaloid, from plants of the Fumariaceae family.

0.1 to 10 μM increase the binding of 3H-GABA with receptors in rat synaptosomes.


- Ko et al., Jap. J. Pharmacol. (1992) 58:1

- Kardos et al., Arzneim-Forsch.(1986) 36(6):939-940



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