CAS No. :

Product Details
Cat No:R067548
Molecular Formula:C21H39NO2
Molecular Weight:337.5
Price:Get quote
We would like to match the lowest price on market if possible.

Your information is safe with us.

Cat No:R067548
N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Linoleoyl ethanolamide (LOEA) has potential signaling roles in aging and neurological functioning. LOEA has a weak affinity for cannabinoid (CB) receptors (Ki = 10 and 25 μM for CB1 and CB2, respectively). It also inhibits fatty acid amide hydrolase (FAAH; Ki = 9 μM) and is hydrolyzed by FAAH, and inhibits voltage-gated K (S)-(−)-Linoleyl-1’-hydroxy-2’-propylamide is a homolog of LOEA, characterized by the addition of an (S)-α-methyl group at the methylene carbon adjacent to the amide nitrogen. A similar modification of arachidonoyl ethanolamide (Item No. 90050) to produce S-1 methanandamide (Item No. 90072) results in a diminished affinity for the CB receptor but greatly improved metabolic stability to aminopeptidase hydrolysis. The physiological actions of this compound have not been evaluated.
1.Lucanic, M.,Held, J.M.,Vantipalli, M.C., et al. N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans. Nature 473(7346), 226-229 (2011).
Recommended Products
  • CAS No. :1219803-22-1
    Product Name:


    Cat No: R050297 View details
  • CAS No. :95-76-1
    Product Name:


    Cat No: R050298 View details
  • CAS No. :99300-67-1
    Product Name:

    4’-Hydroxy Torsemide

    Cat No: R050299 View details
  • CAS No. :1309935-97-4
    Product Name:

    4’-Hydroxy Torsemide-d7

    Cat No: R050300 View details