| Cat No: | R067508 |
| Cas No: | 24880-40-8 |
| Product-Name: | ω-3 Arachidonic Acid |
| InChI: | InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13H,2,5,8,11,14-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12- |
| InChIKey: | HQPCSDADVLFHHO-LTKCOYKYSA-N |
| SMILES: | CC/C=CC/C=CC/C=CC/C=CCCCCCCC(=O)O |
ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 Fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders. In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.
1.Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. American Journal of Clinical Nutrition 54, 438-463 (1991).
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