(+)-Catechin (hydrate)


CAS No. : 225937-10-0

(+)-Catechin (hydrate),225937-10-0
Product Details
Cat No:R067355
Synonyms:D-(+)-Catechin;Catechuic Acid;Cyanidol
Molecular Formula:C15H14O6 · XH2O
Molecular Weight:290.3
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Cat No:R067355
Cas No:225937-10-0
Product-Name:(+)-Catechin (hydrate)
InChI:InChI=1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1
InChIKey:OFUMQWOJBVNKLR-NQQJLSKUSA-N
SMILES:OC1=CC([C@@H](O2)[C@@H](O)CC3=C2C=C(O)C=C3O)=CC=C1O.O
Catechin is a polyphenolic flavonoid which has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro assays of lipid peroxidation. Catechin inhibits the free radical-induced oxidation of isolated LDL by AAPH. It has also been reported to act as an inhibitor of COX-1 with an IC50 of about 80 µM. Catechin and other related procyanidin compounds have antitumor activity when tested in a two-stage mouse epidermal carcinoma model employing topical application.
1.Zhao, J.,Wang, J.,Chen, Y., et al. Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3/'-gallate as the most effective antioxi
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