CAS No. : 71030-37-0

Product Details
Cat No:R067261
Synonyms:(±)12-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid
Molecular Formula:C20H32O3
Molecular Weight:320.473
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Cat No:R067261
Cas No:71030-37-0
IUPAC Name:(5Z,8Z,10E,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid
(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers (Item Nos. 34560 and 34570). It aggregates neutrophils with an EC50 value of 40 nM.
1.O/'Flaherty, J.T.,Thomas, M.J.,Lees, C.J., et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. American Journal of Pathology 104, 55-62 (1981).
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