(±)5-HETE


CAS No. : 73307-52-5

(±)5-HETE,73307-52-5
Product Details
Cat No:R067251
Synonyms:(±)5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
Molecular Formula:C20H32O3
Molecular Weight:320.473
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Cat No:R067251
Cas No:73307-52-5
Product-Name:(±)5-HETE
IUPAC Name:(6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid
InChI:InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+
InChIKey:KGIJOOYOSFUGPC-XTDASVJISA-N
SMILES:CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)O
(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. It contains equal amounts of 5(S)-HETE and 5(R)-HETE. (±)5-HETE induces the aggregation of isolated neutrophils with an IC50 value of 200 nM.
1.O/'Flaherty, J.T.,Thomas, M.J.,Lees, C.J., et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. American Journal of Pathology 104, 55-62 (1981).
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