CAS No. : 90780-53-3

Product Details
Cat No:R067243
Synonyms:13-hydroxy Docosahexaenoic Acid;(±)13-HDoHE
Molecular Formula:C22H32O3
Molecular Weight:344.495
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Cat No:R067243
Cas No:90780-53-3
IUPAC Name:13-hydroxydocosa-4,7,10,14,16,19-hexaenoic acid
(±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Fresh water hydra was shown to metabolize DHA to 13(R)-HDHA, presumably via the 11R-lipoxygenase activity. (±)13-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
1.VanRollins, M. and Murphy, R.C. Autooxidation of docosahexaenoic acid: Analysis of ten isomers of hydroxydocosahexaenoate. J. Lipid Res. 25(5), 507-517 (1984).
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