(±)8-HDHA


CAS No. : 90780-54-4

(±)8-HDHA,90780-54-4
Product Details
Cat No:R067236
Synonyms:8-hydroxy Docosahexaenoic Acid;(±)8-HDoHE
Molecular Formula:C22H32O3
Molecular Weight:344.495
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Cat No:R067236
Cas No:90780-54-4
Product-Name:(±)8-HDHA
IUPAC Name:8-hydroxydocosa-4,6,10,13,16,19-hexaenoic acid
InChI:InChI=1S/C22H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-15-18-21(23)19-16-13-14-17-20-22(24)25/h3-4,6-7,9-10,12-16,19,21,23H,2,5,8,11,17-18,20H2,1H3,(H,24,25)
InChIKey:ZHBVYDMSPDDAKE-UHFFFAOYSA-N
SMILES:CCC=CCC=CCC=CCC=CCC(C=CC=CCCC(=O)O)O
(±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)8-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
1.VanRollins, M. and Murphy, R.C. Autooxidation of docosahexaenoic acid: Analysis of ten isomers of hydroxydocosahexaenoate. J. Lipid Res. 25(5), 507-517 (1984).
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