(±)12(13)-EpOME


CAS No. :

(±)12(13)-EpOME,
Product Details
Cat No:R067144
Synonyms:(±)12,13-EODE;iso-Leukotoxin;(±)-Vernolic Acid
Molecular Formula:C18H32O3
Molecular Weight:296.5
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Cat No:R067144
Product-Name:(±)12(13)-EpOME
InChI:InChI=1S/C18H32O3/c1-2-3-10-13-16-17(21-16)14-11-8-6-4-5-7-9-12-15-18(19)20/h8,11,16-17H,2-7,9-10,12-15H2,1H3,(H,19,20)/b11-8-/t16-,17+/m1/s1
InChIKey:CCPPLLJZDQAOHD-GJGKEFFFSA-N
SMILES:CCCCC[C@@H]1[C@@H](O1)C/C=CCCCCCCCC(O)=O
(±)12(13)-EpOME is the 12,13-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. The toxicity and biosynthesis of (±)12(13)-EpOME have not been well differentiated from (±)9(10)-EpOME (Item No. 52400), but have been presumed to be essentially the same.
1.Hayakawa, M.,Sugiyama, S.,Takamura, T., et al. Neutrophils biosynthesize leukotoxin, 9,10-epoxy-12-octadecenoate. Biochemical and Biophysical Research Communications 137, 424-430 (1986).
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