(±)-Epinephrine (hydrochloride)


CAS No. : 329-63-5

(±)-Epinephrine (hydrochloride),329-63-5
Product Details
Cat No:R066947
Synonyms:(±)-Adrenaline;DL-Adrenaline;DL-Epinephrine
Molecular Formula:C9H14ClNO3
Molecular Weight:219.665
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Cat No:R066947
Cas No:329-63-5
Product-Name:(±)-Epinephrine (hydrochloride)
IUPAC Name:4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride
InChI:InChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H
InChIKey:ATADHKWKHYVBTJ-UHFFFAOYSA-N
SMILES:CNCC(C1=CC(=C(C=C1)O)O)O.Cl
(±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively). Through these receptors, (±)-epinephrine may induce either contraction or relaxation of vascular smooth muscle, depending on adrenoceptor subtype expression. Receptor-mediated actions of (±)-epinephrine are also relevant to blocking anaphylaxis, reversing cardiac arrest, and reducing bleeding in clinical trials.
1.Rothman, R.B.,Vu, N.,Partilla, J.S., et al. In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine transporter substrates. J. Pharmacol. Exp. Ther. 307(
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